Heather Doherty

Heather Doherty
Assistant Professor of Molecular Genetics
Graduate Program Advisor
Phone: (603) 535-3181
E-mail: hedoherty@plymouth.edu

Profile

Dr. Heather Doherty received her training at UNC-Chapel Hill from Dr. Nobuyo Maeda and Nobel
Laureate Dr. Oliver Smithies. While at UNC, Dr. Doherty was trained in tissue culture methods,
pathology, genetic animal models of human disease, cardiovascular biology and advanced statistical methods. Since her arrival at PSU in Fall of 2012, Dr. Doherty has established tissue culture facilities at PSU and begun mentoring students in techniques in mammalian cell culture. Her research interests include mechanisms of tissue scarring in cardiovascular disease, understanding gene networks, human genetic diversity, and the gene connective tissue growth factor. Following cardiovascular disease related damage, the heart can scar similar to skin scarring after a cut or scratch. There are few treatments available to prevent or treat scarring of the heart. Dr. Doherty is interested in the molecular pathways that cause scarring in the heart in order to develop better treatments for cardiovascular disease. As Co-Director of the Biotechnology program, Dr. Doherty is also researching best methods for training students to be independent researchers.

Degrees and Education
  • PhD, Genetics and Molecular Biology, University of North Carolina – Chapel Hill
  • BS, Biology/Genetics, Purdue University
Research Interests
  • Molecular Pathways of Tissue Scarring
  • Cardiovascular Disease
  • Human Genetic Diversity
  • Function and Dynamics of Genetic Networks
Awards and Distinctions
  • Awardee, Plymouth State University RAC Grant 2013
Associations, Boards, and Committees
  • Co-Director, Biotechnology Program
  • Phi Beta Kappa Member
  • Aplha Chi Sigma Member
Recent Publications
  • James LR, Le C, Doherty H, Kim H-S, Maeda N. Connective Tissue Growth Factor (CTGF) Expression Modulates Response to High Glucose. PLoS ONE. 2013 August; 12. 8(8): e70441.
  • Doherty HE, Kim HS, Hiller S, Sulik KK, Maeda N. Altering the Ctgf-3′UTR to make a mouse with low and high basal gene expression. PLoS ONE. 2010 Sept; 22. 5(9): e12909.
  • Altenburg M, Homeister J, Doherty H, Maeda N. Genetics of atherosclerosis in murine models.
    Curr Drug Targets. 2007 Nov;8(11):1161-71.
  • Bell TA, de la Casa-Esperon E, Doherty HE, Ideraabdullah F, Kim K, Wang Y, Lange L, Wilhemsen K, Lange E, Sapienza C, Pardo-Manuel de Villena F. The paternal gene of the DDK syndrome maps to the Schlafen gene cluster on mouse chromosome 11. Genetics. 2006 Jan;172(1):411-23. Epub 2005 Sep 19.
  • Kim K, Thomas S, Howard IB, Bell TA, Doherty HE, Ideraabdullah F, Detwiler DA, Pardo-Manuel de Villena F. Meiotic drive at the Om locus in wild derived mouse inbred strains. Biol J Linnean Soc. Volume 84, Issue 3, Page 487-492, March 2005.

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